Biohacking Longevity
- Sana Lifestyle
- 2 days ago
- 2 min read
Women generally live longer than men, a pattern supported by extensive scientific evidence across global populations. This longevity advantage for women is observed worldwide and has deep evolutionary roots.
Global 2023–2025 data:
• Average global life expectancy for females 76–76.4 years.
• In many high-income countries, the gap is about 5–6 years, with the gap widening in places due to preventable causes.
Key Scientific Reasons for Women’s Longevity Advantage:
1. Women have two X chromosomes. The second X provides a “backup” — if one copy has a harmful mutation or defect, the other can compensate (via processes like X-inactivation).
2. Oestrogen (more prominent pre-menopause) offers protective effects, including better cardiovascular health (reducing oxidative stress, inflammation, and improving cholesterol profiles), stronger immune responses, and potentially slower cellular aging (e.g., slower telomere shortening).
3. Women engage in healthier habits: better diets, less tobacco and alcohol use, more regular medical check-ups, and lower rates of risky behaviours.
4. In many species, females live longer — often by about 13%.
5. Women often show stronger innate/adaptive immunity, better resistance to oxidative damage, and more efficient DNA repair. Paradoxically, women may experience more chronic morbidity (illness) in later life despite longer lifespan — the “mortality-morbidity paradox.”
Stacking Longevity Habits:
In “Blue Zones” like Okinawa (Japan), where women often reach the highest ages, lifestyle amplifies longevity. To boost lifespan AND health span incorporate:
- Plant-based, nutrient-dense diets - no processed food, limit red meat & include phytoestrogen-rich foods (50–80 mg/day) isoflavones for menopausal symptoms/ bone/metabolic health.
- Social connections
- Natural, regular movement & strength training
- Low stress & optimised sleep
- Annual screenings
- Limit alcohol & smoking
- Preventative care
Tip:
Small, consistent changes compound. Focus on sustainable habits over quick fixes; consult healthcare providers for personalisation, especially post-menopause or if you have conditions.
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